RAB17 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 232 amino acids (1-212) and having a molecular mass of 25.6 kDa.The RAB17 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
RAB17 is a member of the small GTPase superfamily which are found in several intracellular compartments and have a significant regulatory part in membrane trafficking. RAB17 regulates traffic throµgh the apical recycling endosome, which indicates that RAB17 has a role in polarized arrangement in epithelial cells.
RAB17 member RAS oncogene family, ras-related protein Rab-17, FLJ12538.
RAB17 is supplied as a sterile filtered clear solution.
RAB17 protein 0.5mg/ml is supplied in 20mM Tris-HCL, pH-8, 0.1M NaCl, 1mM DTT and 30% Glycerol.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.