RAB5B Human-Member RAS Oncogene Family

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RAB5B Human

Qty


Total
$65
Catalog #
PRPS-063
Size
Description
RAB5B Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 238 amino acids (1-215 a.a.) and having a molecular mass of 26.1kDa. The RAB5B is purified by proprietary chromatographic techniques.
Additional Information
IntroductionRas-related protein Rab-5B (RAB5B) belongs to the Rab family of small (monomeric) G proteins. RAB5B is involved in endocytosis and recycling of cell surface molecules. RAB5B interacts with RIN2 and RIN3, which regulate its function, possibly by acting as GEFs. Knockdown of RAB5B abolished group I metabotropic glutamate receptor (mGluR)-mediated neuroprotection.
SynonymsRas-related protein Rab-5B, RAB5B.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe RAB5B solution (1 mg/ml), 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 20% glycerol and 0.2M NaCl.
StabilityRAB5B should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSMTSRSTA
RPNGQPQASK
ICQFKLVLLG
ESAVGKSSLV
LRFVKGQFHE
YQESTIGAAF
LTQSVCLDDT
TVKFEIWDTA
GQERYHSLAP
MYYRGAQAAI
VVYDITNQET
FARAKTWVKE
LQRQASPSIV
IALAGNKADL
ANKRMVEYEE
AQAYADDNSL
LFMETSAKTA
MNVNDLFLAI
AKKLPKSEPQ
NLGGAAGRSR
GVDLHEQSQQ
NK
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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