RAB5B Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 238 amino acids (1-215 a.a.) and having a molecular mass of 26.1kDa. The RAB5B is purified by proprietary chromatographic techniques.
Ras-related protein Rab-5B (RAB5B) belongs to the Rab family of small (monomeric) G proteins. RAB5B is involved in endocytosis and recycling of cell surface molecules. RAB5B interacts with RIN2 and RIN3, which regulate its function, possibly by acting as GEFs. Knockdown of RAB5B abolished group I metabotropic glutamate receptor (mGluR)-mediated neuroprotection.
Ras-related protein Rab-5B, RAB5B.
Sterile Filtered colorless solution.
The RAB5B solution (1 mg/ml), 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 20% glycerol and 0.2M NaCl.
RAB5B should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.