RRM2 Human-Reductase

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RRM2 Human

Qty


Total
$65
Catalog #
ENPS-530
Size
Description
RRM2 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 409 amino acids (1-389 a.a.) and having a molecular mass of 47 kDa. The RRM2 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionRRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis RRM2 is regulated in a cell-cycle dependent method. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RRM2 Inhibits Wnt signaling.
SynonymsEC 1.17.4.1, RR2M, RR2, Ribonucleotide Reductase M2, R2, RRM2.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationRRM2 Human containing 20mM Tris HCL pH-8, 0.1M NaCl, & 10% glycerol.
StabilityRRM2 Human althoµgh stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MLSLRVPLAP
ITDPQQLQLS
PLKGLSLVDK
ENTPPALSGT
RVLASKTARR
IFQEPTEPKT
KAAAPGVEDE
PLLRENPRRF
VIFPIEYHDI
WQMYKKAEAS
FWTAEEVDLS
KDIQHWESLK
PEERYFISHV
LAFFAASDGI
VNENLVERFS
QEVQITEARC
FYGFQIAMEN
IHSEMYSLLI
DTYIKDPKER
EFLFNAIETM
PCVKKKADWA
LR
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished forLABORATORY RESEARCHUSEONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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