SEPSECS Human-Synthase

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SEPSECS Human

Qty


Total
$65
Catalog #
ENPS-040
Size
Description
SEPSECS produced in E.Coli is a single, non-glycosylated polypeptide chain containing 521 amino acids (1-501a.a.) and having a molecular mass of 57.9kDa.SEPSECS is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionSEPSECS catalyzes the last step of sec synthesis by way of converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor. Furthermore, SEPSECS protein is considered a specific marker of autoimmune hepatitis.
SynonymsSLA, SLA/LP autoantigen, SLA-p35, Selenocysteinyl-tRNA(Sec) synthase, Selenocysteine synthase, Liver-pancreas antigen, Soluble liver antigen, Sec synthase, UGA suppressor tRNA-associated protein.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationThe SEPSECS protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 1mM DTT, 100mM NaCl and 10% glycerol.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MNRESFAAGE
RLVSPAYVRQ
GCEARRSHEH
LIRLLLEKGK
CPENGWDEST
LELFLHELAI
MDSNNFLGNC
GVGEREGRVA
SALVARRHYR
FIHGIGRSGD
ISAVQPKAAG
SSLLNKITNS
LVLDIIKLAG
VHTVANCFVV
PMATGMSLTL
CFLTLRHKRP
KAKYIIWPRI
DQKSCFKSMI
TAGFEPVVIE
NVLEGDELRT
DLKAVEAKVQ
EL
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
StorageStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Background

N/A

Protocol

N/A

MSDS
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