TNC Human-Cardiac Troponin

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TNC Human

Qty


Total
$65
Catalog #
PRPS-329
Size
Description
Recombinant Human TNC produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 18,020 Dalton.The TNC is purified by proprietary chromatographic techniques.
Additional Information
IntroductionTroponin is a fundamental regulatory protein of striated muscle contraction, and together with tropomyosin, is positioned on the actin filament. Troponin has 3 subunits: TnI- the inhibitor of actomyosin ATPase; TnT- contains the binding site for tropomyosin; and TnC- the protein encoded by the TNNC1 gene. The binding of calcium to TnC stops the inhibitory action of TnI, consequently allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in the TNNC1 gene are linked to cardiomyopathy dilated type 1Z.
SynonymsTroponin C slow skeletal and cardiac muscles, TN-C, TNNC1, TNNC, TNC, CMD1Z.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationThe protein solution contains 150mM NaCl, 10mM sodium phosphate, 0.05% NaN3, pH 7.0.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
PurityGreater than 95.0% as determined by both:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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