TNNI2 Human, His-Cardiac Troponin

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TNNI2 Human, His

Qty


Total
$65
Catalog #
PRPS-1290
Size
Description
TNNI2 Human Recombinant produced in E. coli is a single polypeptide chain containing 202 amino acids (1-182) and having a molecular mass of 23.5 kDa. TNNI2 is fused to 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionTroponin I, fast skeletal muscle (TNNI2), belongs to the troponin I gene family, and a part of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. TNNI2 is also suppresses tumor growth in human ovarian carcinoma. Mutations in TNNI2 cause myopathy and distal arthrogryposis type 2B.
SynonymsAMCD2B, DA2B, FSSV, fsTnI, Troponin I, fast skeletal muscle, Troponin I, fast-twitch isoform.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe TNNI2 solution (0.25mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 2M Urea, 20% glycerol and 0.2M NaCl.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGDEEKRNRA
ITARRQHLKS
VMLQIAATEL
EKEESRREAE
KQNYLAEHCP
PLHIPGSMSE
VQELCKQLHA
KIDAAEEEKY
DMEVRVQKTS
KELEDMNQKL
FDLRGKFKRP
PLRRVRMSAD
AMLKALLGSK
HKVCMDLRAN
LKQVKKEDTE
KERDLRDVGD
WRKNIEEKSG
MEGRKKMFES
ES.
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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