Urokinase (UK) is a serine protease, which is one of biological plasminogen activators. It is involved in a number of biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. It can be obtained from human urine or kidney cell culture.
Sterile Filtered White lyophilized (freeze-dried) powder.
The Urokinase was lyophilized from a concentrated (1mg/ml) solution containing phosphate buffer.
It is recommended to reconstitute the lyophilized Urokinase in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Lyophilized Urokinase althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Urokinase should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.
Greater than 92.0% as determined by SDS-PAGE.
NeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
1. Title:Transient ?-catenin stabilization modifies lineage output from human thymic CD34+CD1a– progenitors. Publication:Published online before print December 1, 2009, doi: 10.1189/jlb.0509344 March 2010 Journal of Leukocyte Biology vol. 87 no. 3 405-414 .Link:http://www.jleukbio.org/content/87/3/405.full2.Title:Activation of human pro-urokinase by unrelated proteases secreted by Pseudomonas aerµginosa.Publication:Received 26 November 2009/18 March 2010; accepted 2Link:http://www.biochemj.org/bj/428/0473/bj4280473.htm