AKR1B10 Human-Reductase

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AKR1B10 Human

Qty


Total
$65
Catalog #
ENPS-423
Size
Description
AKR1B10 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 316 amino acids (1-316 a.a) and having a molecular mass of 36 kDa. The AKR1B10 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionAKR1B10 efficiently reduces aliphatic and aromatic aldehydes, and it is less active on hexoses. AKR1B10 is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. AKR1B10 is a monomeric protein that competently catalyzes the reduction of aromatic and aliphatic aldehydes and ketones. AKR1B10 is widely expressed in numerous human tissues, small intestine, colon and adrenal gland. AKR1B10 is pathogenically involved in diabetic complications and is overexpressed in human tumors, such as liver, breast, and lung cancer, AKR1B10 is involved in the development and progression of cancer.
SynonymsHIS, HSI, ARL1, ARL-1, ALDRLn, AKR1B11, AKR1B12, MGC14103, AKR1B10, Aldo-keto reductase family 1 member B10, Aldose reductase-like, Aldose reductase-related protein, ARP, hARP, Small intestine reductase, SI reductase.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear colorless solution.
FormulationThe AKR1B10 solution contains 20mM Tris-HCl pH-8 and 10% glycerol.
StabilityAKR1B10 Recombinant Human althoµgh stable at 4°C for 30 days, should be stored desiccated below -20°C for periods greater than 30 days. Please avoid freeze-thaw cycles.
Amino Acid SequenceMATFVELSTK
AKMPIVGLGT
WKSPLGKVKE
AVKVAIDAGY
RHIDCAYVYQ
NEHEVGEAIQ
EKIQEKAVKR
EDLFIVSKLW
PTFFERPLVRKAFEKTLKDL
KLSYLDVYLI
HWPQGFKSGD
DLFPKDDKGN
AIGGKATFLD
AWEAMEELVD
EGLVKALGVS
NFSHFQIEKL
LNKPGLKYKP
VTNQVECHPY
LTQEKLIQYC
HSKGITVTAY
SPLGSPDRPW
AKPEDPSLLE
DPK
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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