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Home / SERVICES / Peptide Services / Peptide synthesis
- SERVICES
- FRATURES
- QA/QC
- PUBLICATIONS
- MODIFICATION
NeoPeptide™ has a more than 400,000 sqf state of the art facility with peptide synthesizers, HPLCs, and mass spectrometers capable of producing over 10,000 peptides/month. We offer a comprehensive range of Peptide Synthesis Services from peptide sequence design to complex peptide modifications. We provide the highest quality peptide synthesis at the most competitive prices. All our peptides come with a complete quality control package, which includes HPLC and MS Analysis.
| ADVANTAGE | NEOPEPTIDE | COMPETITORS |
|---|---|---|
| Hight success rate | ≥ 98% | ≤ 75% |
| Economical Prices | rate | From |
| Quotations | Get an instant quote | day(s) |
| TFA Removal Service | Yes | No |
| Advanced synthesis platform | Yes | No |
- High Success Rate: >98%
- Fast Turnaround Time: 2-3 weeks
- Length: up to 200 amino acids
- Quantities: from mg to kg scale
- Purities: up to 99%
- Peptide conjugation: BSA, KLH, others
- Competitive Prices: 30% below market prices
- Numerous peptide modifications available
- Flexible choices for Liquid Phase Peptide Synthesis (LPPS)
- • Used for short peptides
- Research and Large-Scale Solid Phase Peptide Synthesis (SPPS)
- • Used for longer, more complex sequences
- Proprietary Ligation Technology
- • Allows the joining of up to 200 amino acids
- Microwave Technologies
- • Increases chemical coupling efficiency, enhances success rate, and improves yield
Certificate of Analysis includes MS and HPLC analyses performed after the completion of peptide synthesis, purification, and QC (quality control) steps. These analyses are followed by independent QA (quality assurance) procedures, guaranteeing the highest quality of peptides.
- Chromatography (HPLC, TLC, GC, IC)
- Chromatography coupled to MS (LC-MS/ESI)
- Spectroscopy (UV-Vis, IR, NMR)
- Refractometry
- Polarimetry
- Metallic Analysis (AAS, ICP, ICP-MS)
- Elemental Analysis
- Titration (Acid-Base Titration, Karl Fischer Titration)
- Amino acid analysis
- For quotations, please use our online quotation form, and you may also contact us by email (sales@neoscientific.com),
- or phone (888-754-5670, or +1617-500-7103), fax (1-888-754-5670)
- Please use our online peptide synthesis ordering system and either a PO (Purchase Order) or credit card
- Our customer service representatives are available 24 hours, Monday through Friday to assist you.
Customer Publications (seleted)
NeoPeptide™ Synthesis Services have helped thousands of scientists publish their research in peer-reviewed journals.
Clin Vaccine Immunol.
Jun 2013; 20(6): 789–794. PMCID: PMC3675979 Comparative Efficacy of Two Leading Candidate Ricin Toxin A Subunit Vaccines in Mice
J Biol Chem.
Jun 21, 2013; 288(25): 18243–18248. PMCID: PMC3689966 α7 Helix Region of αI Domain Is Crucial for Integrin Binding to Endoplasmic Reticulum Chaperone gp96
NeoPeptide™ designs different synthetic strategies depending on the peptide sequences in order to fit various specifications. We offer a wide range of peptide modification services including but not limited to the following:
AMIDATION (C-TERMINUS) OR ACETYLATION (N-TERMINUS)
Acetylation (N-Terminal), HYNIC (N-Terminal), DTPA (N-Terminal), Formylation (N-Terminal), Fatty acid (N-Terminal), Myristic acid (N-Terminal), Palmytolyl (N-Terminal), Benzyloxycarbonylation (CBZ), Amidation (C-Terminal), Succinylation (Suc, N-Terminal), etc.
SPECIAL AMINO ACIDS
D-Arg, D-Cys, D-Asp, D-Asn, D-Glu, D-Gln, D-Ser, D-His, D-Thr, D-Trp, D-Leu,D-Ile, D-Met, D-Pro, D-Val ,D-Phe, pGlu, Hyp, D-Lys,D-Tyr, D-Orn, Orn, Abu, Aib, (D)1-Nal, (D)2-Pal, (D)4-Cl-Phe, Nva, Nle, Hse, Hcy, Pen, Mpa,N-Methyl amino acid (Ala, Phe, Leu, Ile, Val, Gly, Met),Other amino acid, Dinitrobenzoylation (Lys), Lys (Me2), Phosphorylation (Tyr, Ser, Thr, single site), Tyr(SO3H2), Ser (octanoic acid), etc.
FLUORESCENCE/DYE LABELING
Biotin (N-Terminal, Y/N Ahx), Biotin (Lys in sequence), Biotin (without Lys in sequence), FITC/5-FAM (N-Terminal, Y/N Ahx), Dansyl (N-Terminal, Y/N Ahx), MCA (N-Terminal), p-Nitroanilide (pNA, C-Terminal), AMC (C-Terminal)
MULTIPLE DISULFIDE BONDS
NeoPeptideTM is able to build up to three disulfide bridges between cysteine at specified positions on one peptide.
MULTIPLE PHOSPHORYLATIONS
NeoPeptideTM can synthesize serine-, threonine-, and tyrosine-phosphopeptides. For peptides containing one or more of these hydroxy-amino acids, selective phosphorylation can be achieved by orthogonal protection or by Fmoc-protected phosphorylated amino acids.
KEYHOLE LIMPET HEMOCYANIN (KLH), BOVINE SERUM ALBUMIN (BSA), AND OVALBUMIN
To generate significant immune responses, peptides are conjugated to bigger carrier proteins, such as ovalbumin, or BSA or KLH. NeoPeptideTM couples the cysteine residue of the peptide to the carrier protein.
PEGYLATION
PEGylation is the covalent conjugation of macromolecules with polyethylene glycol (PEG), polymers that are nonionic, nontoxic, biocompatible and highly hydrophilic. PEGylation enhances the therapeutic application of macromolecules.
ISOTOPE LABELING
NeoPeptideTM can label peptides with stable nonradioactive isotopes, such as 2H, 15N, 13C, or both 15N and 13C.
MULTIPLE ANTIGENIC PEPTIDE (MAP) SYSTEM
Multiple antigenic peptides, consisting of highly localized peptide density and high molecular weight, is one potent way to produce high-titer antipeptide antibodies and synthetic peptide vaccines. This system utilizes lysine to form a backbone to which multiple peptide chains can be attached. NeoPeptideTM can form Asymmetric 4 branches and Asymmetric 8 branches.
QUENCHED FLUORESCENT PEPTIDE
Abz/ Tyr (3-NO2), EDANS/DABCYL