DNAJB11 Human-Heat Shock Protein

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DNAJB11 Human

Qty


Total
$65
Catalog #
HYPS-049
Size
Description
DNAJB11 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 357 amino acids (23-358 a.a.) and having a molecular mass of 40.5kDa.DNAJB11 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionDNAJB11 is a member of the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJB11 serves as a co-chaperone for HSPA5 and binds directly to both unfolded proteins which are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed.
SynonymsDnaJ homolog subfamily B member 11, APOBEC1-binding protein 2, ABBP-2, DnaJ protein homolog 9, ER-associated DNAJ, ER-associated Hsp40 co-chaperone, ER-associated dnaJ protein 3, ERdj3, ERj3p, HEDJ, Human DnaJ protein 9, hDj-9, PWP1-interacting protein 4,
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe DNAJB11 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGRDFYKILG
VPRSASIKDI
KKAYRKLALQ
LHPDRNPDDP
QAQEKFQDLG
AAYEVLSDSE
KRKQYDTYGE
EGLKDGHQSS
HGDIFSHFFG
DFGFMFGGTP
RQQDRNIPRG
SDIIVDLEVT
LEEVYAGNFV
EVVRNKPVAR
QAPGKRKCNC
RQEMRTTQLG
PGRFQMTQEV
VCDECPNVKL
VNEERTLEVE
IEPGVRDGME
YPFIGEGEPH
VD
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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