GADD45GIP1 Human-DNA-Damage Protein

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GADD45GIP1 Human

Qty


Total
$65
Catalog #
PRPS-979
Size
Description
GADD45GIP1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 196 amino acids (48-222) and having a molecular mass of 22.6 kDa.GADD45GIP1 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionGADD45GIP1 is a nuclear protein which takes part in apoptosis control. GADD45GIP1 is expressed in several tissues, such as heart, thyroid, trachea, kidney, ovary, pancreas, testis and stomach and acts as a negative regulator of G1 to S phase cell cycle production by collaborating with GADD45 proteins to inhibit the activity of cyclin-dependent kinases.
SynonymsGrowth arrest and DNA-damage-inducible gamma interacting protein 1, PRG6, CRIF1, PLINP-1, KBBP2, Plinp1, Papillomavirus L2-interacting nuclear protein 1, CKII beta-associating protein, CR6-interacting factor 1, p53-responsive gene 6 protein, CKII beta bin
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe GADD45GIP1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 0.2M NaCl and 40% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MPRWQLGPRY
AAKQFARYGA
ASGVVPGSLW
PSPEQLRELE
AEEREWYPSL
ATMQESLRVK
QLAEEQKRRE
REQHIAECMA
KMPQMIVNWQ
QQQRENWEKA
QADKERRARL
QAEAQELLGY
QVDPRSARFQ
ELLQDLEKKE
RKRLKEEKQK
RKKEARAAAL
AAAVAQDPAA
SGAPSS
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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