MIF Human-Macrophage Migration Inhibitor

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MIF Human

Qty


Total
$65
Catalog #
CYPS-582
Size
Description
MIF human Recombinant was cloned into an E. coli expression vector and was purified to apparent homogeneity by using conventional column chromatography techniques.Macrophage Inducing Factor Human Recombinant is a single, non-glycosylated, polypeptide chain containing 115 amino acids and having a molecular mass of 12 kDa.
Additional Information
IntroductionThe cytokine Macrophage Migration Inhibitor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration.
SynonymsPhenylpyruvate tautomerase, Glycosylation-inhibiting factor, GIF, MMIF, MIF.
SourceEscherichia Coli.
Formulation1mg/ml solution containing 50mM Tris-HCl pH-8, 0.5mM DTT & 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMPMFIVNTNV
PRASVPDGFL
SELTQQLAQA
TGKPPQYIAV
HVVPDQLMAF
GGSSEPCALC
SLHSIGKIGG
AQNRSYSKLL
CGLLAERLRI
SPDRVYINYY
DMNAANVGWN
NSTFA.
PurityGreater than 98.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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