Myostatin Propeptide Human-Myostatin

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Myostatin Propeptide Human

Qty


Total
$65
Catalog #
CYPS-455
Size
Description
Recombinant Human Myostatin Propeptide is a 27.8 kDa protein containing 244 amino acid residues of the human Myostatin Propeptide.
Additional Information
IntroductionMyostatin (GDF-8), a member of the TGFbeta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70%) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo.
SynonymsGDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered white lyophilized (freeze-dried) powder.
FormulationLyophilized from 10mM Acetic Acid.
SolubilityIt is recommended to reconstitute the lyophilized Myostatin Propeptide in sterile 50mM Acetic Acid at 0.1 mg/ml, which can then be further diluted to other aqueous solutions.
StabilityStore lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time.
Amino Acid SequenceMNENSEQKE
NVEKEGLCNA
CTWRQNTKSS
RIEAIKIQIL
SKLRLETAPN
ISKDVIRQLL
PKAPPLRELI
DQYDVQRDDS
SDGSLEDDDY
HATTETIITM
PTESDFLMQV
DGKPKCCFFK
FSSKIQYNKV
VKAQLWIYLR
PVETPTTVFV
QILRLIKPMK
DGTRYTGIRS
LKLDMNPGTG
IWQSIDVKTV
LQNWLKQPES
NLGIEIKALD
ENGHDLAVTF
PGPGEDGLNP
FLE
PurityGreater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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