PKC-b I Human-Protein Kinase-C

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PKC-b I Human

Qty


Total
$65
Catalog #
PKPS-325
Size
Description
PKC-bI Human Recombinant produced in Sf9 is a glycosylated, polypeptide chain containing amino acids 2-671 and having a molecular mass of 80 KD. This protein is the full-length form of the protein with an amino terminal poly His-tag.PKC-bI is purified by proprietary chromatographic techniques.
Additional Information
IntroductionProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sµgar absorption. Studies in mice also sµggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
SynonymsProtein kinase C beta type, EC 2.7.11.13, PKC-beta, PKC-B, PRKCB1, PKCB, PRKCB, PRKCB2, MGC41878.
SourceSf9 insect cells.
FormulationPKC-bI is supplied at a of 0.1mg/ml in 10mM Tris, pH 7.4, 0.1M NaCl, 20% glycerol, 1mM DTT, 0.1mM EDTA, 0.2mM PMSF and 0.03% Brij-35.
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
StorageStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Background

N/A

Protocol

N/A

MSDS
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