Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion throµgh viscous mediums such as mucus. Treponema pallidum subsp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation throµgh genome reduction to the rich environment of mammalian tissue.
8M urea, 20mM Tris-HCl pH-8 and 10mM B-ME.
Treponema Pallidum protein is >90% pure as determined by 10% PAGE (coomassie staining).
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Treponema Pallidum protein is suitable for ELISA and Western blots, excellent antigen for detection of T.Pallidum with minimal specificity problems.
Treponema Pallidum althoµgh stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Treponema Pallidum proteinwas purified by proprietary chromatographic technique.
Immunoreactive with sera of T.Pallidum infected individuals.