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Home / PRODUCTS / Catalog Antibodies / Polyclonal Antibodies
- SPECIFICATION
- BACKGROUND
- DOCUMENTS
- REVIEW
ADDITIONAL INFORMATION
SYNONYMS
hbeta1; BKbeta1; SLO-BETA; hslo-beta; K(VCA)beta; slo-beta-1; k(VCA)beta-1; KCNMB1
REACTIVITY
Human
TESTED APPLICATIONS
ELISA,WB
RECOMMENDED DILUTION
WB,1:200 - 1:2000
CALCULATED MW
22kDa
OBSERVED MW
18kDa
IMMUNOGEN
Recombinant fusion protein containing a sequence corresponding to amino acids 30-102 of human KCNMB1 (NP_004128.1).
POSITIVE SAMPLES
U-87MG,THP-1,MCF7
CELLULAR LOCALIZATION
Membrane,Multi-pass membrane protein,
STORAGE BUFFER
Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
BACKGROUND
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.
REVIEW
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