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Home / PRODUCTS / Catalog Antibodies / Polyclonal Antibodies
- SPECIFICATION
- BACKGROUND
- DOCUMENTS
- REVIEW
ADDITIONAL INFORMATION
SYNONYMS
KSR; RSU2; KSR1
REACTIVITY
Human,Mouse,Rat
TESTED APPLICATIONS
ELISA,WB,IF/ICC
RECOMMENDED DILUTION
WB,1:500 - 1:2000|IF/ICC,1:50 - 1:100
CALCULATED MW
102kDa
OBSERVED MW
110kDa
IMMUNOGEN
Recombinant fusion protein containing a sequence corresponding to amino acids 320-420 of human KSR1 (NP_055053.1).
POSITIVE SAMPLES
U-251MG,HeLa,Jurkat,mouse brain,mouse spleen,mouse testis,mouse kidney,mouse lung,rat brain
CELLULAR LOCALIZATION
Cytoplasm,Endoplasmic reticulum membrane,Membrane,Peripheral membrane protein,
STORAGE BUFFER
Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
BACKGROUND
Enables 14-3-3 protein binding activity; ATP binding activity; and protein C-terminus binding activity. Involved in positive regulation of MAPK cascade. Located in endoplasmic reticulum and membrane. Part of protein-containing complex. Implicated in breast adenocarcinoma. Biomarker of breast cancer.
REVIEW
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