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Home / PRODUCTS / Catalog Antibodies / Monoclonal Antibodies
- SPECIFICATION
- BACKGROUND
- DOCUMENTS
- REVIEW
ADDITIONAL INFORMATION
SYNONYMS
GSTT1
REACTIVITY
Human,Mouse,Rat
TESTED APPLICATIONS
ELISA,WB
RECOMMENDED DILUTION
WB,1:1000 - 1:5000
CALCULATED MW
27kDa
OBSERVED MW
27kDa
IMMUNOGEN
Recombinant protein of human GSTT1.
POSITIVE SAMPLES
HepG2,Mouse Liver,Mouse kindey,Rat Brain,Rat Liver
CELLULAR LOCALIZATION
Cytoplasm,
STORAGE BUFFER
Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
BACKGROUND
The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants.
REVIEW
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