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| Reactivity | Human Mouse |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:1000 IHC 1:10 - 1:50 IF 1:10 - 1:50 |
| Calculated MW | 42kDa |
| Observed MW | Refer to Figures |
| Immunogen | A synthetic peptide of human ACTC1 |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | b |
| Synonym | ACTC; ASD5; CMD1R; CMH11; LVNC4 |
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
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