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| Reactivity | Human Mouse Rat |
| Tested applications | IHC |
| Recommended Dilution | IHC 1:20 - 1:100 |
| Calculated MW | 41kDa |
| Observed MW | Refer to Figures |
| Immunogen | A synthetic peptide of human AGTR2 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | b |
| Synonym | AT2; ATGR2; MRX88 |
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
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