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| Reactivity | Human Mouse Rat |
| Tested applications | WB |
| Recommended Dilution | WB 1:200 - 1:2000 |
| Calculated MW | 96kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human AHR |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | bk |
| Synonym | HLHe76 |
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been largely regarded as a mediator of xenobiotic metabolism [PMID:18483242]. It plays a part role in physiologic activities, including attenuation of the acute phase response, cytokine signaling, T helper (TH)17 immune cell differentiation, modulation of NF-κB activity, and regulation of hormonal signaling [PMID:20423157,18540824]. It also mediates transcription factor sequestering away from a gene promoter or tethering of the AhR to a transcription factor on a promoter.
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