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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IP |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:20 - 1:50 |
| Calculated MW | 55 kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human ALDH1A1 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e; |
Immunohistochemistry of paraffin-embedded mouse brain using ALDH1A1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver using ALDH1A1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human kidney using ALDH1A1 antibody at dilution of 1:100 (40x lens).
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.
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