APEH-Polyclonal Antibodies

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APEH

Qty


Total
$220
Catalog #
A5893
Antibody Type
Polyclonal Antibody
Gene ID
327
Swiss Prot
P13798
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100
Calculated MW81kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human APEH
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationj
SynonymAPH; OPH; AARE; ACPH; D3S48E; D3F15S2; DNF15S2;
Images
  • A5893: image 1

    Western blot analysis of extracts of various cell lines, using APEH antibody.

  • A5893: image 2

    Immunofluorescence analysis of HeLa cell using APEH antibody. Blue: DAPI for nuclear staining.

Background

This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Protocol

N/A

MSDS
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