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Reactivity | Human Mouse Rat |
Tested applications | WB IHC IP |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:20 - 1:200 IP 1:20 - 1:50 |
Calculated MW | 38kDa |
Observed MW | Refer to figures |
Immunogen | A synthetic Peptide of human ARMC10 |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]
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