ARRB2-Polyclonal Antibodies

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ARRB2

Qty


Total
$220
Catalog #
A0142
Antibody Type
Polyclonal Antibody
Gene ID
409
Swiss Prot
P32121
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Calculated MW46kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human ARRB2
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationm
SynonymARB2; ARR2; BARR2;
Images
  • A0142: image 1

    Western blot analysis of extracts of RAW264.7 cell line, using ARRB2 antibody.

Background

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Protocol

N/A

MSDS
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