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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Calculated MW | 21kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human BNIP3 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | bc |
| Synonym | NIP3; |
Western blot analysis of extracts of various cell lines, using BNIP3 antibody.
Immunohistochemistry of paraffin-embedded mouse kidney using BNIP3 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded rat heart using BNIP3 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human liver injury using BNIP3 antibody at dilution of 1:100 (x40 lens).
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2.
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