CALM3-Monoclonal Antibodies

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CALM3

Qty


Total
$220
Catalog #
A1161
Antibody Type
Polyclonal Antibody
Gene ID
808
Swiss Prot
P62158
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200
Calculated MW17kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human CALM3
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationdi
SynonymCALM3;PHKD;PHKD3 ;
Images
  • A1161: image 1

    Western blot analysis of brain cell lysate using CALM3 antibody.

Background

Calmodulin is a ubiquitously expressed small protein mediating many cellular effects such as short-term and long-term memory, nerve growth, inflammation, apoptosis, muscle contraction and intracellular movement (1). Upon binding of four Ca2+ ions, calmodulin undergoes conformational changes, allowing this complex to bind to and activate many enzymes including protein kinases, protein phosphatases, ion channels, Ca2+ pumps, nitric oxide synthase, inositol triphosphate kinase, and cyclic nucleotide phosphodiesterase (2,3). Since calmodulin binds Ca2+ in a cooperative fashion, small changes in cytosolic Ca2+ levels lead to large changes in the level of active calmodulin and its target proteins (4).

Protocol

N/A

MSDS
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