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+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-617.299.7367 (Int’l)
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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Calculated MW | 28kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human CAPNS1 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | 30K; CANP; CDPS; CSS1; CANPS; CAPN4; CALPAIN4; |
Western blot analysis of extracts of various cell lines, using CAPNS1 antibody.
Immunohistochemistry of paraffin-embedded human liver cancer using CAPNS1 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human colon using CAPNS1 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human esophageal cancer using CAPNS1 antibody at dilution of 1:100 (x40 lens).
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
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