CBX8-Polyclonal Antibodies

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CBX8

Qty


Total
$220
Catalog #
A2682
Antibody Type
Polyclonal Antibody
Gene ID
57332
Swiss Prot
Q9HC52
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200
Calculated MW43kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human CBX8
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationfl
SynonymPC3; RC1;
Images
  • A2682: image 1

    Western blot analysis of extracts of various cell lines, using CBX8 antibody.

Background

Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.CBX8 has been shown to interact with RING1 and MLLT1.Component of a Polycomb group (PcG) multiprotein PRC1-like complex; a complex class required to maintain the transcriptionally repressive state of many genes; including Hox genes; throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119'; rendering chromatin heritably changed in its expressibility.

Protocol

N/A

MSDS
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