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Reactivity | Human Mouse |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 |
Calculated MW | 47kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human CCBL1 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | GTK; KAT1; KATI; |
Western blot analysis of extracts of various cell lines, using CCBL1 antibody.
Immunohistochemistry of paraffin-embedded mouse liver using CCBL1 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded mouse heart using CCBL1 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of HeLa cell using CCBL1 antibody. Blue: DAPI for nuclear staining.
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
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