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Reactivity | Human Rat |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
Calculated MW | 11kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human CCL11 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | SCYA11; |
Immunohistochemistry of paraffin-embedded rat lung using CCL11 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using CCL11 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using CCL11 antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of A549 cell using CCL11 antibody. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of A549 cell using CCL11 antibody. Blue: DAPI for nuclear staining.
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
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