|Tested applications||WB IHC FC|
|Recommended Dilution||WB 1:500 - 1:2000
IHC 1:50 - 1:100
FC1:20 - 1:50|
|Observed MW||Refer to Figures|
|Immunogen||A synthetic peptide of human CCNE1|
|Storage Buffer||Store at 4℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Synonym||CCNE; Cyclin E1;|
Cyclin E1 (CCNE1) is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. CCNE1, an essential cyclin activating Cdk2, regulates the G1-S phase transition of the mammalian cell division cycle. Its timing expression plays a direct role in the initiation of DNA replication , the control of histone biosynthesis, and the centrosome cycle. CCNE1 is associated with disease progression in various malignancies and is associated clinically with poor prognosis.
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