CCT3-Polyclonal Antibodies

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CCT3

Qty


Total
$220
Catalog #
A6547
Antibody Type
Polyclonal Antibody
Gene ID
7203
Swiss Prot
P49368
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Calculated MW60kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human CCT3
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymCCTG; PIG48; TRIC5; CCT-gamma; TCP-1-gamma;
Images
  • A6547: image 1

    Western blot analysis of extracts of various cell lines, using CCT3 antibody.

  • A6547: image 2

    Immunohistochemistry of paraffin-embedded mouse heart using CCT3 antibody at dilution of 1:100 (x40 lens).

  • A6547: image 3

    Immunofluorescence analysis of U20S cell using CCT3 antibody. Blue: DAPI for nuclear staining.

Background

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8.

Protocol

N/A

MSDS
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