CD3E-Polyclonal Antibodies

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CD3E

Qty


Total
$380
Catalog #
A10786
Antibody Type
Monoclonal Antibody
Gene ID
916
Swiss Prot
P07766
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB IHC IP FC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:20 - 1:50 FC 1:20 - 1:50
Calculated MW23 kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human CD3E
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymT3E; TCRE; IMD18;
Images
  • A10786: image 1

    Immunohistochemistry of paraffin-embedded human spleen using CD3E antibody at dilution of 1:100 (40x lens).

  • A10786: image 2

    Immunohistochemistry of paraffin-embedded human tonsil using CD3E antibody at dilution of 1:100 (40x lens).

Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Protocol

N/A

MSDS
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