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Reactivity | Human Mouse |
Tested applications | WB IHC FC |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 FC1:20 - 1:50 |
Calculated MW | 55kDa |
Observed MW | Refer to Figures |
Immunogen | A synthetic peptide of human CD4 |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | CD4mut; |
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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