CD79A-Monoclonal Antibodies

our services
our products
Quotations & Ordering:

For quotations, please use our online quotation form, and you may also contact us by

[email protected]

Phone:

+1-888.733.6849
+1-617.299.7367 (Int’l)
+44-203.695.3777 (UK)

Fax:

+1-888.733.6849
+1-617.299.7367 (Int’l)

Our customer service representatives are available 24 hours, Monday through Friday to assist you.

CD79A

Qty


Total
$220
Catalog #
A0332
Antibody Type
Monoclonal Antibody
Gene ID
973
Swiss Prot
P11912
Size
Species
Mouse
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Calculated MW44/48kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human CD79A
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymGA;MB-1;B-cell antigen receptor complex-associated protein alpha chain antibody;
Images
  • A0332: image 1

    Western blot analysis of extracts of Raji cell line, using CD79A antibody.

Background

CD79a (mb-1/ B lymphocyte-specific MB-1 protein) was originally identified on the basis of its restricted expression in lymphocytes of B lineage. CD79a associates with surface IgM-receptors; it has been implicated in the signal transduction pathways and in the regulation of type of type 2A-related serine/threonine phosphatases catalytic activity. A disulphide-linked heterodimer, consisting of CD79a (mb-1) and CD79b / B29 polypeptides, non-covalently associates with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79 is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also CD79 interacts with and increases activity of some Src-family tyrosine kinases.

Protocol

N/A

MSDS
Reviews
Neo Scientific welcomes feedback from its customers.

If you have used an our product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information.

If you have any additional inquiries please email technical services at [email protected].

Thank you for your support.

promotions

Image

Custom Monoclonal Antibody
MassAb Technologies
Image
Free Trial Custom Polyclonal Antibody
You will receive free purified antibodies for validation
Image
Custom Peptides Synthesis

Start from $40/each

new technologies

Image
Optimized for enhanced
expression levels
XPromoter 2.0
Image
E.coli/insect cells/293 & CHO

3 in 1 expression system
Image
MassAb Technologies

Cover All Epitopes