|Tested applications||WB IHC ICC IF IP FC|
|Recommended Dilution||WB 1:500 - 1:2000
IHC 1:50 - 1:200
ICC 1:50 - 1:200
IF 1:50 - 1:100
IP 1:20 - 1:50
FC 1:20 - 1:50|
|Calculated MW||70 kDa|
|Observed MW||Refer to figures|
|Immunogen||Recombinant protein of human CD86|
|Storage Buffer||Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Synonym||B70; B7-2; B7.2; LAB72; CD28LG2;|
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
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