CDH1-Methylated Antibodies

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CDH1

Qty


Total
$220
Catalog #
A11492
Antibody Type
Polyclonal Antibody
Gene ID
999
Swiss Prot
P12830
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200
Calculated MW135kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human CDH1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymCDH1; Arc-1;CD324 ;CDHE ; ECAD;LCAM ; UVO ;E-Cad/CTF3 ;Uvomorulin; E-Cadherin;
Images
  • A11492: image 1

    Immunohistochemistry of paraffin-embedded human esophagus using CDH1 antibody at dilution of 1:100 (40x lens).

  • A11492: image 2

    Immunohistochemistry of paraffin-embedded human stomach using CDH1 antibody at dilution of 1:100 (40x lens).

Background

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]

Protocol

N/A

MSDS
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