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Reactivity | Human Mouse Rat |
Tested applications | WB IHC ICC IP |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 ICC 1:50 - 1:200 IP 1:20 - 1:50 |
Calculated MW | 33 kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human CDK2 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | CDKN2; p33(CDK2); |
Immunohistochemistry of paraffin-embedded mouse spleen using CDK2 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human tonsil using CDK2 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human spleen using CDK2 antibody at dilution of 1:100 (40x lens).
Immunofluorescence
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants.
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