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Reactivity | Human Rat |
Tested applications | WB IHC IP |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IP1:20 - 1:50 |
Calculated MW | 39kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human CDK7 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | e |
Synonym | CAK1; HCAK; MO15; STK1; CDKN7; p39MO15; |
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
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