CFH-Polyclonal Antibodies

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CFH

Qty


Total
$220
Catalog #
A1360
Antibody Type
Polyclonal Antibody
Gene ID
3075
Swiss Prot
P08603
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:50
Calculated MW180kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human CFH
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymFH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3;
Images
  • A1360: image 1

    Western blot analysis of extracts of A549 cell line, using CFH antibody.

Background

CFH (Complement factor H) is a member of the Regulator of Complement Activation (RCA) gene cluster and a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this CFH have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy (1).

Protocol

N/A

MSDS
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