CFHR1-Polyclonal Antibodies

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CFHR1

Qty


Total
$220
Catalog #
A2743
Antibody Type
Polyclonal Antibody
Gene ID
3078
Swiss Prot
Q03591
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200
Calculated MW38kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human CFHR1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymCFHL; FHR1; HFL1; HFL2; CFHL1; H36-1; H36-2; CFHL1P; CFHR1P;
Images
  • A2743: image 1

    Western blot analysis of extracts of Mouse liver tissue, using CFHR1 antibody.

  • A2743: image 2

    Immunohistochemistry of paraffin-embedded human liver cancer tissue using CFHR1antibody.

Background

This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Protocol

N/A

MSDS
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