COX7A2L-Tag and Loading control Antibodies

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COX7A2L

Qty


Total
$220
Catalog #
A8298
Antibody Type
Polyclonal Antibody
Gene ID
9167
Swiss Prot
O14548
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Calculated MW13kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human COX7A2L
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymEB1; SIG81; COX7AR; COX7RP;
Images
  • A8298: image 1

    Western blot analysis of extract of various cells, using COX7A2L antibody.

Background

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.

Protocol

N/A

MSDS
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