CPS1-Monoclonal Antibodies

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CPS1

Qty


Total
$220
Catalog #
A8080
Antibody Type
Polyclonal Antibody
Gene ID
1373
Swiss Prot
P31327
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB
Recommended DilutionWB 1:1000 - 1:2000
Calculated MW165kDa
Observed MWRefer to figures
ImmunogenRecombinant Protein of human CPS1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymPHN; CPSASE1;
Images
  • A8080: image 1

    Western blot analysis of extracts of various cell lines, using CPS1 antibody.

Background

The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.

Protocol

N/A

MSDS
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