CST3-Polyclonal Antibodies

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CST3

Qty


Total
$220
Catalog #
A1561
Antibody Type
Polyclonal Antibody
Gene ID
1471
Swiss Prot
P01034
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:10 - 1:100
Calculated MW16kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human CST3
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymARMD11; MGC117328;CST3;
Images
  • A1561: image 1

    Western blot analysis of extracts of various cells, using CST3 antibody.

  • A1561: image 2

    Immunohistochemistry of paraffin-embedded human prostate using CST3 antibody at dilution of 1:100 (40x lens).

  • A1561: image 3

    Immunofluorescence analysis of HeLa cell using CST3 antibody. Blue: DAPI for nuclear staining.

Background

Cystatin C is a 14 kDa member of the Cystatin superfamily of cysteine protease inhibitors (1). Most cell types secrete Cystatin C (1). Cystatin C inhibits cathepsins, and thereby may function as a tumor suppressor by inhibiting cathepsin mediated tumor cell invasion (2). In addition, this tumor suppressor function can also be attributed to Cystatin C's ability to antagonize TGF-β1 signaling (2,3). Cystatin C may also modulate antigen presentation through its ability to inhibit cathepsins (4). Cystatin C is also a biomarker for kidney dysfunction (5).

Protocol

N/A

MSDS
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