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Reactivity | Human Rat |
Tested applications | WB IHC FC |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 FC1:20 - 1:50 |
Calculated MW | 39kDa |
Observed MW | Refer to Figures |
Immunogen | A synthetic peptide of human CXCR4 |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | ab |
Synonym | FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E; |
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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