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Reactivity | Human Mouse |
Tested applications | WB |
Recommended Dilution | WB 1:500 - 1:1000 |
Calculated MW | 58kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human CYP11B2 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | CPN2; ALDOS; CYP11B; CYP11BL; CYPXIB2; P450C18; P-450C18;P450aldo; |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
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