CYP1A2-Polyclonal Antibodies

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CYP1A2

Qty


Total
$220
Catalog #
A0062
Antibody Type
Polyclonal Antibody
Gene ID
1544
Swiss Prot
P05177
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityMouse Rat
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Calculated MW58kDa
Observed MWRefer to Figures
ImmunogenRecombinant Protein of human CYP1A2
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymCP12; P3-450; P450(PA);
Images
  • A0062: image 1

    Western blot analysis of extracts of various cells, using CYP1A2 antibody.

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Protocol

N/A

MSDS
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