CYP3A4-Polyclonal Antibodies

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CYP3A4

Qty


Total
$220
Catalog #
A2544
Antibody Type
Polyclonal Antibody
Gene ID
1576
Swiss Prot
P08684
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC FC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 FC 1:20 - 1:100
Calculated MW57kD
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human CYP3A4
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymCP33;CP34;CYP3A;CYP3A3;HLP;MGC126680; NF-25; P450C3; P450PCN1;
Images
  • A2544: image 1

    Western blot analysis of extracts of various cell lines, using CYP3A4 antibody.

  • A2544: image 2

    Immunohistochemistry of paraffin-embedded human liver cancer using CYP3A4 antibody at dilution of 1:100 (400x lens).

Background

Cytochrome P450 3A(CYP3A) belongs to the cytochrome P450 family and the enzymes constitute an important detoxification system that contributes to primary metabolism of more than half of all prescribed medications.CYP3A expression determines impairment of drug absorption and efficient systemic clearance in a tissue-specific manner(PMID:17975676).This antibody is specific to CYP3A4.

Protocol

N/A

MSDS
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