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Reactivity | Human Mouse Rat |
Tested applications | WB IHC |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
Calculated MW | 36kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human DEDD |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | DEFT; KE05; DEDD1; FLDED1; CASP8IP1; |
Immunohistochemistry of paraffin-embedded rat lung using DEDD antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using DEDD antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using DEDD antibody at dilution of 1:100 (40x lens).
This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
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